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Dwaine F Emerich

age ~62

from North Scituate, RI

Also known as:
  • Dwaine Emerich
  • Merid E Dwaine
  • Dwaine Demarco
  • Dwaine Emerrich

Dwaine Emerich Phones & Addresses

  • North Scituate, RI
  • Providence, RI
  • Cranston, RI
  • N Scituate, RI
  • San Bernardino, CA
  • Piscataway, NJ
  • State College, PA
  • Highland Park, NJ
  • 241 Anan Wade Rd, North Scituate, RI 02857

Work

  • Company:
    Incytu, inc.
    2007 to 2010
  • Position:
    Vp research; chief scientific officer

Education

  • Degree:
    PhD
  • School / High School:
    Rutgers, The State University of New Jersey-New Brunswick
    1986 to 1990
  • Specialities:
    Neuroscience

Industries

Biotechnology

Vehicle Records

  • Dwaine Emerich

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  • Address:
    241 Anan Wade Rd, North Scituate, RI 02857
  • Phone:
    401-6479271
  • VIN:
    2HGFG21518H706642
  • Make:
    HONDA
  • Model:
    CIVIC
  • Year:
    2008

Us Patents

  • Pulmonary Delivery In Treating Disorders Of The Central Nervous System

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  • US Patent:
    6514482, Feb 4, 2003
  • Filed:
    Sep 19, 2000
  • Appl. No.:
    09/665252
  • Inventors:
    Raymond T. Bartus - Sudbury MA
    Dwaine F. Emerich - Cranston RI
  • Assignee:
    Advanced Inhalation Research, Inc. - Cambridge MA
  • International Classification:
    A61K 912
  • US Classification:
    424 45, 424 43, 424789, 514220, 12820315
  • Abstract:
    A method of pulmonary delivery of a medicament, for example a dopamine precursor or a dopamine agonist, which includes administering to the respiratory tract of a patient in need of rescue therapy particles comprising an effective amount of a medicament. The particles are delivered to the pulmonary system and are released into the blood stream and delivered to the medicaments site of action in a time sufficiently short to provide the rescue therapy. In addition to the medicament, the particles can include other materials such as, for example, phospholipids, amino acids, combinations thereof and others. Preferred particles have a tap density of less than about 0. 4 g/cm.
  • Implantable Biocompatible Immunoisolatory Vehicle For The Delivery Of Selected Therapeutic Products

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  • US Patent:
    63228041, Nov 27, 2001
  • Filed:
    May 2, 2000
  • Appl. No.:
    9/563248
  • Inventors:
    Keith E. Dionne - Rehoboth MA
    Dwaine F. Emerich - Providence RI
    Diane Hoffman - Cambridge MA
    Paul R. Sanberg - Spring Hill FL
    Lisa Christenson - New Haven CT
    Orion D. Hegre - Green Valley AZ
    David W. Scharp - St. Louis MO
    Paul E. Lacy - Webster Grove MO
    Patrick Aebischer - Lutry,
    Alfred V. Vasconcellos - Cranston RI
    Michael J. Lysaght - E. Greenwich RI
    Frank T. Gentile - Warwich RI
  • Assignee:
    Neurotech S.A. - Evry
  • International Classification:
    A61K 950
    A61K 914
  • US Classification:
    424422
  • Abstract:
    An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to maintain the cells, and a permselective, biocompatible, peripheral region free of the isolated cells, which immunoisolates the core yet provides for the delivery of the secreted product or metabolic function to the individual.
  • Methods For Making Immunoisolatary Implantable Vehicles With A Biocompatible Jacket And A Biocompatible Matrix Core

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  • US Patent:
    58740996, Feb 23, 1999
  • Filed:
    May 24, 1995
  • Appl. No.:
    8/449837
  • Inventors:
    Keith E. Dionne - Rehoboth MA
    Dwaine F. Emerich - Providence RI
    Diane Hoffman - Cambridge MA
    Paul R. Sanberg - Spring Hill FL
    Lisa Christenson - New Haven CT
    Orion D. Hegre - Green Valley AZ
    David W. Scharp - St. Louis MO
    Paul E. Lacy - Webster Grove MO
    Patrick Aebischer - Lutry,
    Michael J. Lysaght - E. Greenwich RI
    Frank T. Gentile - Warwich RI
  • Assignee:
    Brown University Research Foundation
  • International Classification:
    A61K 950
    A61K 914
  • US Classification:
    424422
  • Abstract:
    A method of forming an implantable and retrievable immunoisolatory vehicles is disclosed, the method comprising the steps of first forming a core comprising a volume of at least 1. mu. l and at least 10. sup. 4 cells capable of providing a biologically active product or metabolic or immunologic function, said cells being dispersed in a biocompatible hydrogel or extracellular matrix, and then forming around the core a surrounding external biocompatible thermoplastic or hydrogel jacket free of said cells projecting externally thereof, said jacket having molecular weight cutoff permitting passage of molecules to and from the core through said jacket to provide said biologically active product or function.
  • Methods For Treatment Or Prevention Of Neurodegenerative Conditions Using Immunoisolatory Implantable Vehicles With A Biocompatible Jacket And A Biocompatible Matrix Core

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  • US Patent:
    58717676, Feb 16, 1999
  • Filed:
    May 24, 1995
  • Appl. No.:
    8/449062
  • Inventors:
    Keith E. Dionne - Rehoboth MA
    Dwaine F. Emerich - Providence RI
    Diane Hoffman - Cambridge MA
    Paul R. Sanberg - Spring Hill FL
    Lisa Christenson - New Haven CT
    Orion D. Hegre - Green Valley AZ
    David W. Scharp - St. Louis MO
    Paul E. Lacy - Webster Grove MO
    Patrick Aebischer - Lutry,
    Alfred V. Vasconcellos - Cranston RI
    Michael J. Lysaght - E. Greenwich RI
    Frank T. Gentile - Warwich RI
  • Assignee:
    Brown University Research Foundation
  • International Classification:
    A61K 950
    A61K 914
  • US Classification:
    429422
  • Abstract:
    A method for treatment of a neurodegenerative condition in a patient comprising implanting in the patient at least one immunoisolatory vehicle comprising a corc comprising a volume of at least 1. mu. l and at least 10. sup. 4 living cells which secrete at least one biologically active product, said cells being dispersed in a biocompatible matrix comprising a hydrogel or extracellular matrix components, and an external jacket surrounding the core, the jacket comprising a biocompatible hydrogel or thermoplastic, the jacket being free of cells projecting externally thereof, said jacket having a molecular weight cutoff permitting the passage of the biologically active product from the core through the jacket.
  • Delivery Of Biologically Active Molecules Using Cells Contained In Biocompatible Immunoisolatory Capsules

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  • US Patent:
    56392753, Jun 17, 1997
  • Filed:
    May 25, 1995
  • Appl. No.:
    8/449756
  • Inventors:
    Edward E. Baetge - Barrington RI
    Joseph P. Hammang - Barrington RI
    Frank T. Gentile - Warwick RI
    Mark D. Lindner - Bristol RI
    Shelley R. Winn - Smithfield RI
    Dwaine F. Emerich - Providence RI
  • Assignee:
    CytoTherapeutics, Inc. - Providence RI
  • International Classification:
    A61K 922
    C12N 1500
    C12N 500
    A01N 6300
  • US Classification:
    6048911
  • Abstract:
    This invention provides improved devices and methods for long-term, stable expression of a biologically active molecule using a biocompatible capsule containing genetically engineered cells for the effective delivery of biologically active molecules to effect or enhance a biological function within a mammalian host. The novel capsules of this invention are biocompatible and are easily retrievable. This invention specifically provides improved methods and compositions which utilize cells transfected with recombinant DNA molecules comprising DNA sequences coding for biologically active molecules operatively linked to promoters that are not subject to down regulation in vivo upon implantation into a mammalian host. Furthermore, the methods of this invention allow for the long-term, stable and efficacious delivery of biologically active molecules from living cells to specific sites within a given mammal. In addition, this invention provides a general means for maintaining, for extended periods of time, the in vivo expression of transgenes.
  • Compositions For The Delivery Of Biologically Active Molecules Using Genetically Altered Cells Contained In Biocompatible Immunoisolatory Capsules

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  • US Patent:
    62649418, Jul 24, 2001
  • Filed:
    Jan 25, 1999
  • Appl. No.:
    9/236246
  • Inventors:
    Edward E. Baetge - Barrington RI
    Joseph P. Hammang - Barrington RI
    Frank T. Gentile - Warwick RI
    Mark D. Lindner - Bristol RI
    Shelley R. Winn - Smithfield RI
    Dwaine F. Emerich - Providence RI
  • Assignee:
    Neurotech S.A. - Evry
  • International Classification:
    A61K 4800
    A61K 952
  • US Classification:
    424 9321
  • Abstract:
    This invention provides improved devices and methods for long-term, stable expression of a biologically active molecule using a biocompatible capsule containing genetically engineered cells for the effective delivery of biologically active molecules to effect or enhance a biological function within a mammalian host. The novel capsules of this invention are biocompatible and are easily retrievable. This invention specifically provides improved methods and compositions which utilize cells transfected with recombinant DNA molecules comprising DNA sequences coding for biologically active molecules operatively linked to promoters that are not subject to down regulation in vivo upon implantation into a mammalian host. Furthermore, the methods of this invention allow for the long-term, stable and efficacious delivery of biologically active molecules from living cells to specific sites within a given mammal. In addition, this invention provides a general means for maintaining, for extended periods of time, the in vivo expression of transgenes.
  • Encapsulated Pc12 Cell Transplants For Treatment Of Parkinson's Disease

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  • US Patent:
    58533850, Dec 29, 1998
  • Filed:
    Aug 26, 1994
  • Appl. No.:
    8/296967
  • Inventors:
    Dwaine F. Emerich - Providence RI
    Patrick Aebischer - Lutry,
    Jeffrey H. Kordower - Oak Park IL
  • Assignee:
    CytoTherapeutics, Inc. - Lincoln RI
  • International Classification:
    A61M 3100
  • US Classification:
    604 49
  • Abstract:
    This invention relates to implantation of encapsulated PC12 cells capable of slowing or preventing the degenerative processes of Parkinson's disease by releasing factors in addition to dopamine into individuals suffering from the disease. This restorative effect continues even after the encapsulated cells are removed from the patient's brain.
  • Implantable Biocompatible Immunoisolatory Vehicle For Delivery Of Selected Therapeutic Products

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  • US Patent:
    58008284, Sep 1, 1998
  • Filed:
    Jan 10, 1994
  • Appl. No.:
    8/179151
  • Inventors:
    Keith E. Dionne - Rehoboth MA
    Dwaine F. Emerich - Providence RI
    Diane Hoffman - Cambridge MA
    Paul R. Sanberg - Spring Hill FL
    Lisa Christenson - New Haven CT
    Orion D. Hegre - Green Valley AZ
    David W. Scharp - St. Louis MO
    Paul E. Lacy - Webster Grove MO
    Patrick Aebischer - Lutry,
    Alfred V. Vasconcellos - Cranston RI
    Michael J. Lysaght - E. Greenwich RI
    Frank T. Gentile - Warwich RI
  • Assignee:
    Brown University Research Foundation
  • International Classification:
    A61K 950
    A61K 914
  • US Classification:
    424422
  • Abstract:
    Immunoisolatory vehicles having a core and a surrounding jacket are disclosed, the core having a volume in excess of 1. mu. l and at least about 10. sup. 4 living cells capable of secreting a biologically active product or of providing a biological function to a patient, the cells dispersed in a biocompatible matrix formed of a hydrogel or an extracellular matrix component, and the external jacket being permselective, biocompatible and having a molecular weight cutoff permitting passage of molecules between the patient and the core through said jacket to provide said biological product or function.

Isbn (Books And Publications)

Providing Pharmacological Access to the Brain: Alternate Approaches

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Author
Dwaine F. Emerich

ISBN #
0121852911

Cellular Transplantation: From Laborabory to Clinic

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Author
Dwaine F. Emerich

ISBN #
0123694159

Resumes

  • Dwaine Emerich Photo 1

    Vp Research At Incytu, Inc.

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  • Position:
    VP Research; Chief Scientific Officer at InCytu, Inc.
  • Location:
    Providence, Rhode Island Area
  • Industry:
    Biotechnology
  • Work:
    InCytu, Inc. since 2007
    VP Research; Chief Scientific Officer

    Living Cell Technologies 2003 - 2006
    Vice President of Research

    Alkermes 1997 - 2002
    Director of Biological Research

    CytoTherapeutics 1990 - 1996
    Principle Scientist
  • Education:
    Rutgers, The State University of New Jersey-New Brunswick 1986 - 1990
    PhD, Neuroscience

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