Julie Miwa - New York NY, US Nathaniel Heintz - Pehlem Manor NY, US Ayse Begum Tekinay - Clifton NJ, US
A61K 38/00 A61P 25/00
Disclosed herein are compositions and methods for the treatment or prevention of neurological disorders using lynx compounds. The invention further discloses compositions and methods for the modulation of acetylcholine receptor activity.
Lynx, A Novel Family Of Receptor Ligands In The Central Nervous System, Corresponding Nucleic Acids And Proteins And Uses Thereof
The present invention provides a novel family of polypeptides which are ligand-gated channel receptor accessory molecules or ligands, denoted Lynx. This invention provides an isolated polypeptide comprising an amino acid sequence of a Lynx polypeptide in which the amino acid sequence is set forth in SEQ ID NO:2, SEQ ID NO:4 or SEQ ID NO:15, including fragments, mutants, variants, analogs, homologs, or derivatives, thereof. This invention further provides an isolated immunogenic polypeptide comprising an amino acid sequence of a Lynx polypeptide and relates to antibodies of Lynx polypeptides and the use of such antibodies. The invention provides an isolated nucleic acid encoding a polypeptide comprising an amino acid sequence of a Lynx polypeptide. This invention provides pharmaceutical compositions and diagnostic and therapeutic methods of use of the isolated polypeptides and nucleic acids of the present invention. Assays for compounds which mimic, alter or inactivate the polypeptides of the present invention for use in therapy are also provided. The present invention further relates to methods of isolating Lynx polypeptides and the nucleic acids encoding such polypeptides.
Name / Title
Company / Classification
Phones & Addresses
Julie Michiko Miwa President
Ophidion Inc Drug Discovery
235 S Holliston Ave, Pasadena, CA 91106 2265 E Foothill Blvd, Pasadena, CA 91107
U15G 200 Metres 2010 Southern Champs
South of England Under 15 and Under 17 Track & Field Championships Sat...
15 Jun, 2010
Dr. Julie Miwa, Professor at Lehigh Universit...
In Spring 2022, over 100 people were asked: What Matters Most? The con...
Plasticity and Capacity with Dr. Julie Miwa
Plasticity and Capacity with Dr. Julie Miwa Dr. Julie Miwa, Neurosci...
JU JUTSU KAISEN LIVE ACTION - Maki vs Miwa | ...
Directed by Nik Shaw and Yoshi Sudarso Shot by Nik Shaw Stunt Coordina...
YOKO MIWA TRIO | Live at Regattabar
Yoko Miwa Trio | Live at Regattabar, Cambridge MA! This critically acc...
1h 18m 16s
JAPANESE BREAKFAST RECIPE which doesn't hurt ...
JAPANESE BREAKFAST RECIPE! Today, I'm going to introduce salmon mushro...
Yoko Miwa Trio "Sunshine Follows the Rain" @ ...
Yoko Miwa Trio plays "Sunshine Follows the Rain" by Yoko Miwa at the w...