Nancy L Noble

US Patent:

6906026, Jun 14, 2005

Filed:

Jul 5, 2000

Appl. No.:

09/869820

Inventors:

Nancy A. Noble - Salt Lake City UT, US
Wayne A. Border - Salt Lake City UT, US

Assignee:

The University of Research Foundation - Salt Lake City UT

International Classification:

A61K048/00
A61K039/395
A61K038/00

US Classification:

514 2, 514 4, 514 44, 435 4, 435 6, 435 71

Abstract:

The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.

US Patent:

7713924, May 11, 2010

Filed:

Jul 8, 2004

Appl. No.:

10/887378

Inventors:

Nancy A. Noble - Salt Lake City UT, US
Wayne A. Border - Salt Lake City UT, US
Daniel A. Lawrence - Derwood MD, US

Assignee:

University of Utah Research Foundation - Salt Lake City UT
The American National Red Cross - Rockville MD

International Classification:

A61K 38/14
A61K 38/55
A61K 31/401
C12Q 1/68

US Classification:

514 2, 514 4, 514 44, 435 4, 435 6, 435 71

Abstract:

The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.

US Patent:

7763580, Jul 27, 2010

Filed:

Sep 27, 2004

Appl. No.:

10/952361

Inventors:

Nancy A. Noble - Salt Lake City UT, US
Wayne A. Border - Salt Lake City UT, US

Assignee:

University of Utah Research Foundation - Salt Lake City UT

International Classification:

A61K 38/14
A61K 38/55
A61K 31/4164
A61K 31/401
C12Q 1/68

US Classification:

514 2, 514 4, 514 44 A, 435 6, 435375, 435 4, 435 71

Abstract:

The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix, or at least one agent that degrades excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.

US Patent:

20080175848, Jul 24, 2008

Filed:

Oct 30, 2007

Appl. No.:

11/981283

Inventors:

Nancy A. Noble - Salt Lake City UT, US
Wayne A. Border - Salt Lake City UT, US

Assignee:

University of Utah Research Foundation - Salt Lake City UT

International Classification:

A61K 48/00
A61K 31/473
A61K 31/403
A61K 31/401
A61K 39/395

US Classification:

4241461, 514412, 514423, 514 44, 514290

Abstract:

The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix, or at least one agent that degrades excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.

US Patent:

6316258, Nov 13, 2001

Filed:

Dec 15, 1998

Appl. No.:

9/211916

Inventors:

Nancy A. Noble - Salt Lake City UT
Wayne A. Border - Salt Lake City UT

Assignee:

University of Utah - Salt Lake City UT

International Classification:

G01N 3350

US Classification:

435375

Abstract:

The present invention is methods for inhibiting the renin-induced production of TGF. beta. using a renin inhibitory agent to reduce excess accumulation of extracellular matrix in tissue in a subject, and to the use of renin inhibitory agents and additional TGF. beta. inhibitory agents to reduce TGF. beta. production to treat and prevent fibrotic diseases.

Work:

1st Garden Maintenance
Portsmouth
Dec 2009 to Sep 2012
Office Assistant/Receptionist England 1st Caravan Hire Ltd

2006 to 2009
Owner/Director/Partner England- Sharps Bedrooms

2005 to 2007
Sales consultant Realty USA
Ithaca, NY
2002 to 2004
Real Estate Agent Texas Outdoor design Center LLC
Houston, TX
2000 to 2002
Owner /Director Leisure Collections
Houston, TX
1989 to 2000
Chair King The Chair King
Austin, TX
1984 to 1989
manager of the Chair King relocated The Chair King
Houston, TX
1980 to 1984
Positions heldabove at all Chair King locations and leisure Collections- supervisory

Education:

Work:

SIMON PROPERTY GROUP

2008 to 2000
Paralegal SIMON PROPERTY GROUP

2007 to 2008
Legal Assistant LEE AND RYAN ENVIRONMENTAL CONSULTING, INC

2006 to 2007
Federal Contracting Project Coordinator KELLY SERVICES

2006 to 2006
Project Assistant OMNI MANAGEMENT SERVICES, INC

2006 to 2006
Residential Property Manager PULTE HOMES

2002 to 2006
Land Development Coordinator CLASSIC GENERAL CONTRACTORS

2000 to 2002
Project Coordinator

Education:

BROWN MACKIE COLLEGE
Indianapolis, IN
2010 to 2012
Associates Degree in Paralegal Studies Remington College
Colorado Springs, CO
2000 to 2002
Associates Degree in Computer Information Systems

Skills:

Transactional Paralegal, Legal Research, Commercial Loan Closings, Contract Documents, Corporate Documents, Organizational Skills, Budget Maintenance