Nancy A. Noble - Salt Lake City UT, US Wayne A. Border - Salt Lake City UT, US
Assignee:
The University of Research Foundation - Salt Lake City UT
International Classification:
A61K048/00 A61K039/395 A61K038/00
US Classification:
514 2, 514 4, 514 44, 435 4, 435 6, 435 71
Abstract:
The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.
Methods For Treating Conditions Associated With The Accumulation Of Excess Extracellular Matrix
Nancy A. Noble - Salt Lake City UT, US Wayne A. Border - Salt Lake City UT, US Daniel A. Lawrence - Derwood MD, US
Assignee:
University of Utah Research Foundation - Salt Lake City UT The American National Red Cross - Rockville MD
International Classification:
A61K 38/14 A61K 38/55 A61K 31/401 C12Q 1/68
US Classification:
514 2, 514 4, 514 44, 435 4, 435 6, 435 71
Abstract:
The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.
Methods For Treating Conditions Associated With The Accumulation Of Excess Extracellular Matrix
The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix, or at least one agent that degrades excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.
Methods For Treating Conditions Associated With The Accumulation Of Excess Extracellular Matrix
The present invention is methods and compositions for reducing and preventing the excess accumulation of extracellular matrix in a tissue and/or organ or at a wound site using a combination of agents that inhibit TGFβ, or using agents that inhibit TGFβ in combination with agents that degrade excess accumulated extracellular matrix, or at least one agent that degrades excess accumulated extracellular matrix. The compositions and methods of the invention are used to treat conditions such as fibrotic diseases and scarring that result from excess accumulation of extracellular matrix, impairing tissue or organ function or skin appearance in a subject.
Methods For Preventing And Treating Fibrotic Diseases Resulting From Accumulation Of Excess Extracellular Matrix Induced By Tgf.beta. Using Renin Inhibitors
Nancy A. Noble - Salt Lake City UT Wayne A. Border - Salt Lake City UT
Assignee:
University of Utah - Salt Lake City UT
International Classification:
G01N 3350
US Classification:
435375
Abstract:
The present invention is methods for inhibiting the renin-induced production of TGF. beta. using a renin inhibitory agent to reduce excess accumulation of extracellular matrix in tissue in a subject, and to the use of renin inhibitory agents and additional TGF. beta. inhibitory agents to reduce TGF. beta. production to treat and prevent fibrotic diseases.
Business Records
Name / Title
Company / Classification
Phones & Addresses
Nancy Noble
PacCoin Pacific Coin Centre Ltd. Numismatics
PO Box 28178, 2945 Jacklin Rd, Victoria, BC V9B 5E3 250-4784418
1st Garden Maintenance Portsmouth Dec 2009 to Sep 2012 Office Assistant/ReceptionistEngland 1st Caravan Hire Ltd
2006 to 2009 Owner/Director/PartnerEngland- Sharps Bedrooms
2005 to 2007 Sales consultantRealty USA Ithaca, NY 2002 to 2004 Real Estate AgentTexas Outdoor design Center LLC Houston, TX 2000 to 2002 Owner /DirectorLeisure Collections Houston, TX 1989 to 2000 Chair KingThe Chair King Austin, TX 1984 to 1989 manager of the Chair King relocatedThe Chair King Houston, TX 1980 to 1984 Positions heldabove at all Chair King locations and leisure Collections- supervisory
Education:
ALLEN SCHOOL of Health Science Brooklyn, NY 2012 to 2013 certificate of completion upon graduation in June 2013--- 4.0 GPA in Medical Billing and Coding
2007 to 2008 Legal AssistantLEE AND RYAN ENVIRONMENTAL CONSULTING, INC
2006 to 2007 Federal Contracting Project CoordinatorKELLY SERVICES
2006 to 2006 Project AssistantOMNI MANAGEMENT SERVICES, INC
2006 to 2006 Residential Property ManagerPULTE HOMES
2002 to 2006 Land Development CoordinatorCLASSIC GENERAL CONTRACTORS
2000 to 2002 Project Coordinator
Education:
BROWN MACKIE COLLEGE Indianapolis, IN 2010 to 2012 Associates Degree in Paralegal StudiesRemington College Colorado Springs, CO 2000 to 2002 Associates Degree in Computer Information Systems