Victor N Uebele from 7008 Windswept Ln, Norristown, PA 19403, age 53

Isolated Nucleic Acid Molecule(S) Encoding A Human Calcium Sensitive Potassium Channel Subunit Protein Designated Beta2, Encoded Proteins, And Uses Thereof
view source
US Patent:

20050255559, Nov 17, 2005
Filed:

Jun 23, 2005
Appl. No.:

11/159597
Inventors:

Victor Uebele - Wyncote PA, US
Richard Swanson - Lansdale PA, US
Yuan Liu - Lansdale PA, US
Armando LaGrutta - North Wales PA, US
International Classification:

C07H021/04
C12P021/06
C12N015/09
C07K014/705
US Classification:

435069100, 536023500, 530350000, 435320100, 435325000
Abstract:

The present invention is directed to novel human DNA sequences encoding calcium sensitive potassium channel subunits β2, β3a, β3b, β3c, and β3d, the proteins encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and agonists of calcium sensitive potassium channels containing human β2, β3a, β3b, β3c, or β3d subunits and inhibitors and agonists of β3 gene transcription.

Nucleic Acid Molecules Encoding Novel Murine Low-Voltage Activated Calcium Channel Proteins, Designated-Alpha1H, Encoded Proteins And Methods Of Use Thereof
view source
US Patent:

20070178462, Aug 2, 2007
Filed:

Feb 14, 2005
Appl. No.:

10/589702
Inventors:

Victor Uebele - Wyncote PA, US
Thomas Connolly - Lansdale PA, US
International Classification:

C12Q 1/68
G01N 33/567
C07H 21/04
C12P 21/06
C07K 14/705
C07K 16/28
C12N 5/06
US Classification:

435006000, 435007200, 435069100, 435320100, 435353000, 530350000, 536023500, 530388220
Abstract:

Disclosed herein are novel nucleic acid molecules encoding murine low-voltage activated calcium channel proteins, designated-α1H, encoded proteins, vectors, host cells transformed therewith, as well as pharmaceutical compositions. Methods of using any of the foregoing, e.g., methods for screening for candidate agonists or antagonists utilizing the novel protein isoforms are also disclosed.

Novel Human Potassium Channel Beta Subunit
view source
US Patent:

20040058353, Mar 25, 2004
Filed:

Sep 29, 2003
Appl. No.:

10/416413
Inventors:

Donna Cusimano - Lansdale PA, US
Richard Swanson - Lansdale PA, US
Victor Uebele - Wyncote PA, US
International Classification:

C12Q001/68
C07H021/04
C07K014/705
US Classification:

435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:

The present invention is directed to a novel human DNA sequences encoding Kv2.3, a potassium channel subunit, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and agonists of potassium channels containing the human Kv2.3 subunit.

Victor N Uebele